Peer Reviewed Publications:
Cooper, L.M.**, Kavanagh, J.A.*, Hanson, A.*, and Waddell, D.S. Fam83d Modulates MAP Kinase and AKT Signaling and is Induced During Neurogenic Skeletal Muscle Atrophy. Submitted to Cellular Signaling - In revision.
Labuzan, S.A.#,**, Lynch, S.A.#,**, Cooper, L.M.**, and Waddell, D.S. Inhibition of Protein Phosphatase Methylesterease 1 Dysregulates MAP Kinase Signaling and Attentuates Muscle Cell Differentiation. Under review. #These authors contributed equally to this work.
Lynch, S.A.**, McLeod, M.A.*, Orsech, H.C.*, Cirelli, A.M.*, and Waddell, D.S. Zinc Finger Protein 593 is Upregulated During Skeletal Muscle Atrophy and Modulates Muscle Cell Differentiation. Experimental Cell Research. 383(2) 2019. [Epub ahead of print] doi.org/10.1016/j.yexcr.2019.111563
Hayes, C.S.**, Labuzan, S.A.**, Menke, J.A.*, Haddock, A.N.**, and Waddell, D.S. Ttc39c is Upregulated During Skeletal Muscle Atrophy and Modulates ERK1/2 MAP Kinase and Hedgehog Signaling. Journal of Cellular Physiology. 234(12) 2019: 23807-23824. doi.org/10.1002/jcp.28950
Haddock, A.N.**, Labuzan, S.A.**, Haynes, A.E.*, Hayes, C.S.**, Kakareka, K.M.** and Waddell, D.S. Dual-specificity Phosphatase 4 (Dusp4) is Upregulated During Skeletal Muscle Atrophy and Modulates Extracellular Signal-Regulated Kinase (ERK) Activity.# American Journal of Physiology - Cell Physiology. 316(4) 2019: C567-C581. #APSselct Award. doi.org/10.1152/ajpcell.00234.2018
Waddell, D.S., Duffin, P.J.*, Haddock, A.N.**, Triplett, V.E.*, Saredy, J.J.**, Eldredge, J.T.* and Kakareka, K.M.* Isolation, Expression Analysis and Characterization of NEFA Interacting Nuclear Protein 30 and RING Finger and SPRY Domain Containing 1 in Skeletal Muscle. Gene. 576(1) 2016: 319-332. doi.org/10.1016/j.gene.2015.10.046
Furlow, J.D., Watson, M.L., Waddell, D.S., Neff, E.S., Baehr, L.M., Ross, A.P. and Bodine, S.C. Altered Gene Expression Patterns in Muscle Ring Finger 1 Null Mice During Denervation and Dexamethasone Induced Muscle Atrophy. Physiological Genomics. 45(13) 2013: 1168-85. doi.org/10.1152/physiolgenomics.00022.2013
Loucks K., Waddell, D.S., and Ross, C. Lipopolysaccharides Elicit an Oxidative Burst as a Component of the Innate Immune System in the Seagrass Thalassia testudinum. Plant Physiol Biochem. 70 2013: 295-303.
Gomes, A.V., Waddell, D.S., Siu, R., Stein, M., Dewey, S., Furlow, J.D., and Bodine, S.C. Upregulation of Proteasome Activity in Muscle RING Finger 1-null Mice Following Denvervation. FASEB J. 26(7) 2012: 2986-99. doi.org/10.1096/fj.12-204495
Waddell, D.S., Baehr, L.M., van den Brandt, J., Johnsen, S.A., Reichardt, H.M., Furlow, J.D. and Bodine, S.C. The Glucocorticoid Receptor and FoxO1 Synergistically Activate the Skeletal Muscle Atrophy Associated MuRF1 Gene. Am J Physiol Endocrinol Metab. 295(4) 2008: 785-797. doi.org/10.1152/ajpendo.00646.2007
Guo, X., Waddell, D.S.*, Wang, W., Liberati, N.T., Yong, S., Liu, X. and Wang, X-F. Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-b signaling.Oncogene 27(58) 2008: 7235-47. *Co-First Author.
Guo, X., Ramirez, A., Waddell, D.S., Liu, X., and Wang, X-F. Axin and GSK3-β control Smad3 protein stability and modulate TGF-β signaling. Genes and Development 22(1) 2008: 106-120.
Cohen, T.J., Waddell, D.S., Barrientos, T., Lu, Z., Feng, G., Cox, G.A., Bodine, S.C. and Yao, T-P. The Histone Deacetylase HDAC4 Connects Neural Activity to Muscle Transcriptional Reprogramming. J. Biol. Chem. 282(46) 2007: 33752-33759.
Weidner, W.J., Waddell, D.S. and Furlow, J.D. Measurement of the filtration coefficient (Kfc) in the lung of Gallus domesticus and the effects of increased microvascular permeability. J. Comp. Physiol. [B]. 176(6) 2006: 567-74.
Waddell, D.S., Liberati, N.T., Guo, X., Frederick, J.P. and Wang, X-F. A Functional Role for Casein Kinase Iε in the TGF-β Signaling Pathway. J. Biol. Chem. 279(28) 2004: 29236-29246.
Frederick, J.P., Liberati, N.T., Waddell, D.S., Shi, Y. and Wang, X-F. TGF-β Mediated Transcriptional Repression of c-myc is Dependent on Direct Binding of Smad3 to a Novel Repressive Smad Binding Element. Mol. Cell. Biol. 24(6) 2004: 2546-59.
Shen, X., Li, J., Hu, P. P-C., Waddell, D.S., Zhang, J. and Wang, X-F. The Activity of Guanine Exchange Factor Net1 is Essential for TGF-b Mediated Stress Fiber Formation. J. Biol. Chem. 276(18) 2001: 15362-15368.
Weidner, W.J., Waddell, D.S. and Sillman, A.J. Low Levels of Cadmium Chloride Alter the Immunoprecipitation of Corneal Cadherin-Complex Proteins. Archives of Toxicology. Arch. Toxicol. 74(10) 2000: 578-581.
Kim, A.E., Dintaman, J.M., Waddell, D.S. and Silverman, J.A. Saquinavir, an HIV Protease Inhibitor, is Transported by p-Glycoprotein. J Pharmacol Exp Ther. 286(3) 1998: 1349-1445.
